Federal investigators say they have uncovered a key breakthrough in the investigation into the disappearance of 84‑year‑old Nancy Guthrie.

The FBI announced that forensic analysis of evidence, including a glove found near the area where Guthrie was last seen, has produced important DNA leads that were not previously available. Law enforcement sources say this development could help identify suspects or narrow down the list of possible locations.

The glove was recovered about two miles from Guthrie’s home in Tucson, Arizona, and officials are now analyzing genetic material taken from it to see if it matches Guthrie or someone connected to her case.

In addition to the forensic work, the FBI has released enhanced video footage of a person of interest approaching Guthrie’s front door. Investigators hope public recognition of the individual could lead to new tips or a break in the case.

Local authorities and the FBI have been searching the area for weeks after Guthrie’s disappearance, which has drawn nationwide attention, especially since her daughter, NBC News host Savannah Guthrie, appealed for help finding her mother.

Experts say that breakthroughs like DNA evidence can sometimes turn cold cases into leads, but authorities caution that forensic results must still be confirmed and matched before charges can be pursued.

Police continue to ask the public for any information that might help locate Nancy Guthrie or identify anyone involved in her disappearance.