A widely used medication taken by millions for heartburn and acid reflux is now back in focus after new warnings about potential long-term effects.

Omeprazole, part of a group of drugs known as proton pump inhibitors (PPIs), is commonly prescribed to reduce stomach acid and treat conditions like reflux and ulcers.

While it’s considered safe for short-term use, experts say problems may arise when it’s taken for extended periods — especially without medical supervision.

Health professionals have warned that long-term use could interfere with the body’s ability to absorb key nutrients like magnesium, calcium, and vitamin B12.

Over time, this may lead to issues such as weakened bones, low energy levels, or other complications linked to nutrient deficiencies.

There are also concerns about an increased risk of infections, as reduced stomach acid can make it easier for harmful bacteria to grow.

Some research has even suggested a possible link between these medications and other side effects, including headaches or migraines, though more studies are needed to confirm this.

Health guidance typically advises that over-the-counter use should not exceed a short period unless directed by a doctor.

Experts stress that while the medication remains effective and important for many people, it should be used carefully and reviewed regularly.