Rosie O’Donnell is speaking candidly about the health journey that transformed her life, revealing how a GLP-1 medication helped her lose around 60 pounds and why she ultimately chose to undergo a facelift after years of struggling with her weight.

Rosie Calls Mounjaro a ‘Miracle Drug’

The 64-year-old comedian shared that she began taking Mounjaro after being diagnosed with type 2 diabetes three years ago. Since then, she has gradually lost about 60 pounds, describing the medication as life-changing.

O’Donnell said the treatment dramatically reduced what she calls the constant “food noise,” something she had struggled with for most of her life. She added that she wanted to speak openly about using the medication because she doesn’t believe in keeping secrets.

A Lifetime of Weight Struggles

Rosie reflected on how her relationship with food changed after the death of her mother when she was just 10 years old. She recalled that grief and difficult family circumstances led to unhealthy eating habits, which affected everyone in the household.

She said losing weight slowly over several years has helped her feel healthier, stronger, and more confident than she has in a long time.

Why She Chose a Facelift

After the weight loss, O’Donnell decided to undergo a deep plane facelift to address loose skin around her lower face. She explained that pronounced facial lines made her appear sad, even though she felt happy.

The actress said she carefully researched surgeons and wanted natural-looking results rather than appearing dramatically different. She also admitted she wrestled with the decision because of her feminist beliefs before concluding that true feminism means women have the freedom to make their own choices about their bodies.

No Regrets About Being Honest

O’Donnell revealed the procedure cost around $90,000, adding that she wanted to be transparent after people began asking why she looked different.

Rather than pretending nothing had changed, she said she hopes sharing her experience helps others who struggle with obesity or body image realize they are not alone.